(a,b,c,d) Comparison of cognitive function between MMD and healthy controls. Compared with the healthy controls matched by gender, age and education years, the adult MMD without stroke had a wide range of cognitive impairment, including MOCA, HAMD, CDT, TMTA, TMTB, CAVLT1, CAVLT2. Ns: no significant difference; *:0.01<p < 0.05: #p ≤ 0.01.