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. 2022 Nov 24;43(4):581–594. doi: 10.1177/0271678X221142139

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Figure 1. — Example [¹⁸F]MK-6240 PET images and segmentations for the evaluated reference and extracerebral regions. (a) SUV_90–110 PET image for a MCI subject (SUVR_CerGM = 2.1 across target regions) showing characteristic tau uptake pattern in the temporal and occipital lobes. (b) FreeSurfer segmentations of the candidate reference regions overlaid on the SUV_90-110 image. (c) SUV_90-110 PET image for a CN subject (SUVR_CerGM = 1.2 across target regions) showing high extracerebral signal (SUVR_CerGM = 1.4), especially surrounding the brain hemispheres and the cerebellum. Extracerebral masks overlaid on SUV_90-110 PET (d) and MR (e) images.