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. 2023 Mar 16;14:1062630. doi: 10.3389/fphar.2023.1062630

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Copyright © 2023 Lu, Chai, Qiu, Zhang, Wu, Fu, Wang and Qin.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The GO analysis and KEGG pathway enrichment of target mRNAs of differential miRNAs. (A) The top five enrichments from Go terms (BP/CC/MF) for the target mRNAs of upregulated miRNAs. (B) The top five enrichments from Go terms (BP/CC/MF) for the target mRNAs of downregulated miRNAs. (C) The top 10 pathways enriched from KEGG of target mRNAs of upregulated miRNAs. (D) The top 10 pathways enriched from KEGG of the target mRNAs of downregulated miRNAs (p < 0.05). Coloring indicates the p-value with higher values in red and lower values in blue, and the lower p-value indicates that the gene is more significantly enriched. (GO, gene ontology; KEGG, kyoto encyclopedia of genes and genomes; BP, biological processes; MF, molecular function; CC, cellular component).