Table 1.

Average euclidean distance of mental health participants compared to controls.

Group A	Group B	Group A euclidean distance (mean ± sd)	Group B euclidean distance (mean ± sd)	Games-Howell (p-value)
Control participants	Depressive participants	1.41 ± 0.70	2.03 ± 1.02	0.001*
Control participants	Schizophrenic participants	1.41 ± 0.70	1.56 ± 0.83	0.047*
Depressive participants	Schizophrenic participants	1.56 ± 0.83	2.03 ± 1.02	0.001*

Euclidean distance between all points (corresponding to an individual’s UMAP coordinates) within a group were calculated, and within-group average and standard deviation distance quantified. Euclidean distances across groups was compared via Welch’s ANOVA and followed by Games-Howell post-hoc pairwise-comparison to directly assess difference in average distance between the three groups.

^*p ≤ 0.05.