Table 1.
Baseline patient demographics (mean ± SD).
| Variable | Patients n = 203 |
Controls n = 51 |
P Value |
|---|---|---|---|
| Female/Male (male %) | 36/167 (82) | 30/21 (41) | < 0.05 |
| Age at Baseline | 64.7 ± 7.8 | 59.5 ± 7.5 | < 0.05 |
| Number of Pack Years | 28.7 ± 26.0 | 6.1 ± 13.6 | < 0.05 |
| Current smoker (%) | 67 (33) | 7 (14) | < 0.05 |
| Former smoker (%) | 84 (41) | 10 (20) | < 0.05 |
| Never smoker (%) | 52 (26) | 34 (66) | < 0.05 |
| BMI (kg/m2) Derived | 22.9 ± 3.2 | 24.0 ± 3.2 | |
| FEV1 (L) | 1.78 ± 0.70 | 2.28 ± 0.57 | < 0.05 |
| FEV 1 Post (L) | 1.90 ± 0.70 | 2.28 ± 0.60 | < 0.05 |
| FEV1/FVC (%) | 61.6 ± 16.2 | 79.9 ± 5.0 | < 0.05 |
| FRC (L) | 3.96 ± 1.38 | 3.03 ± 0.75 | < 0.05 |
| FVC (L) | 3.00 ± 0.78 | 3.00 ± 0.80 | |
| FVC Post (L) | 3.06 ± 0.74 | 3.00 ± 0.78 | |
| IC (L) | 2.19 ± 0.58 | 2.24 ± 0.56 | |
| RV (L) | 3.25 ± 1.68 | 2.23 ± 0.50 | < 0.05 |
| TLC (L) | 6.14 ± 1.39 | 5.25 ± 1.06 | < 0.05 |
| DLCO (mmol/ kPa x min) | 19.26 ± 5.61 | 22.86 ± 4.46 | < 0.05 |