Table 3.
Univariate logistic regression analysis of risk factors for delayed cognitive recovery at 30 days
| Univariate analysis | Multivariate analysis | |||
|---|---|---|---|---|
| Risk factors | OR(95%CI) | P value | OR(95%CI) | P value |
| Age(age ≥ 70, age<70) | 0.841(0.327–2.163) | 0.719 | ||
| Smoking | 1.077(0.452–2.566) | 0.867 | ||
| Medical history | ||||
| Diabetes mellitus | 2.697(1.060–6.861) | 0.037** | 6.508(2.049–20.664) | 0.001** |
| History of cerebrovascular disease | 5.244(1.828–15.042) | 0.002** | 10.211(2.842–36.688) | <0.001** |
| Previous major surgery history | 3.561(1.245–10.185) | 0.018** | 0.065* | |
| Surgical data | ||||
| VICA(Sevoflurane combined with propofol was used for anesthesia) | 2.302(0.735–7.212) | 0.153* | 5.306(1.272–22.138) | 0.022** |
| Hypotension(MAP ≤ 65mmHg, ≥5 min) | 0.900(0.332–2.437) | 0.836 | ||
|
Perioperative inadvertent hypothermia (< 35℃) |
3.111(1.163–8.322) | 0.024** | 5.688(1.693–19.109) | 0.005** |
| Pre-NLR ≥ 2.5 | 0.797(0.296–2.149) | 0.654 | ||
| NRS (resting) ≥ 4 at 1st day after surgery | 1.187 (0.364–3.869) | 0.776 | ||
Abbreviations: DNR Delayed Neurocognitive Recovery, NRS Numeric Rating Scales, NLR Neutrophil-to-lymphocyte Ratio, VICA Intravenous inhalation combined anesthesia
*P < 0.2, ** P < 0.05.