Table 4.

Univariate logistic regression analysis of risk factors for delayed cognitive recovery on the 4th day

	Univariate analysis		Multivariate analysis
Risk factors	OR(95%CI)	P value	OR(95%CI)	P value
Age (age ≥ 70, age<70)	1.842(0.915–3.710)	0.087*	2.311(1.096–4.876)	0.028**
Smoking	0.831(0.424–1.630)	0.59
Medical history
Diabetes mellitus	2.006(0.897–4.489)	0.09*	1.972(0.845–4.599)	0.116
History of cerebrovascular disease	1.615(0.602–4.332)	0.341
Previous major surgery history	2.337(0.881-6.200)	0.088*	2.126(0.764–5.918)	0.149
Surgical data
VICA(use sevoflurane ≥ 50 min)	1.409(0.512–3.878)	0.507
Hypotension(MAP ≤ 65mmHg)	1.147(0.545–2.416)	0.717
Perioperative inadvertent hypothermia(<35℃)	1.354(0.563–3.255)	0.498
Pre-NLR ≥ 2.5	0.462(0.211–1.012)	0.054*	0.428(0.188–0.975)	0.043**
NRS (resting) ≥ 4 at 1st day after surgery	0.731(0.277–1.932)	0.528

Abbreviations: DNR Delayed Neurocognitive Recovery, NRS Numeric Rating Scales, NLR Neutrophil-to-lymphocyte Ratio, VICA Intravenous inhalation combined anesthesia

*P < 0.2, ** P < 0.05.