Table 1.
Elimination half-times (T1/2) of Au and Ag in organs (days)
| Exposure | AuNP (days) | AuNP + AgNP (days) | AgNP (days) | AuNP + AgNP (days) |
|---|---|---|---|---|
| Measured | Au | Ag | ||
| Lung* | 81.5 | 54.2 |
3.1 (fast) 48.5 (slow) |
2.2 (fast) 28.4 (slow) |
| Liver | 192.60 | 221.4 | 1.4 | 2.5 |
| Kidneys | Accumulation | Accumulation | Accumulation | Accumulation |
| Spleen | 177.0 | Accumulation | Accumulation | NE |
| Testes | NE | Accumulation | Accumulation | Accumulation |
| Epididymis | Accumulation | Accumulation | 29.9 days | Accumulation |
| Olfactory bulb | 20.4 | NE | 75.1 | 17.8 |
| Eyes | 25.8 | NE | 68.7 | 128.6 |
| Brain | NE | NE | Accumulation | 108.9 |
| Hilar lymph nodes | 65.3 | 25.2 | 11.4 | 2.8 |
| Brachial lymph nodes | 10.8 | 11.1 | 59.7 | 53.5 |
| Thymus | 17.7 | NE | 89.5 | Accumulation |
| Blood | 2.2 | NE | NE | NE |
NE, not eliminated; Accumulated, Au or Ag concentration is increased during PEO
*Kim et al. [3]