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. 2022 Jun 2;119(2):599–610. doi: 10.1093/cvr/cvac092

Figure 2.

Figure 2

PHACTR1 coronary artery disease risk allele (GG) did not impact on ex vivo vascular function. Endothelial cell-dependent dilation to acetylcholine (A) GG = 33, GA = 83, and AA = 54 subjects per genotype and bradykinin (B) GG = 17, GA = 35, and AA = 19 subjects per genotype was assessed in saphenous veins there was no difference observed across the genotypes (P > 0.05, two-way ANOVA for repeated measures). (C) Endothelial cell-independent dilation in saphenous veins to sodium nitroprusside (SNP, GG = 35, GA = 80, and AA = 51 subjects per genotype) was not different between genotypes.