Fig. 1.

Antibody responses following AZ, Moderna, and MVC vaccination. Antibody titers were measured in serum collected before vaccination (pre vac) and 4 weeks after the second dose (post 2nd). The presence of S-specific antibodies (anti-S IgG) against WT (A), Delta (B), and Omicron (C) variants in serum was determined by ELISA. The upper panels of Figs. A, B, and C show the antibody titers produced by each individual against the three variants following AZ, Moderna, and MVC vaccines. The lower panels of Figs. A, B and C are the folds of antibody calculated by dividing the antibody titer after the second dose by the prevaccination. (D) The folds of antibodies against WT, Delta and Omicron S protein were compared after AZ, Moderna and MVC vaccination. The numbers in each column on the graph are the means for each group. The results are presented as the means ± SD. p < 0.05 (∗), p < 0.01 (∗∗), p < 0.001 (∗∗∗) and p < 0.0001 (∗∗∗∗).