Fig. 2.

Antibody responses following AZ, Moderna, and MVC vaccination. Competitive activity in serum samples collected from two doses of vaccine was detected by competitive ELISA. The percent inhibition was measured using 10-, 40-, and 80-fold dilutions of serum to compete with WT (A), Delta (B), and Omicron (C) S proteins for binding to ACE2. The upper panels of Figs. A, B, and C show the percent inhibition following AZ, Moderna, and MVC vaccination. The lower panels of Figs. A, B and C show the percentage of inhibition in 40-fold diluted serum from all three vaccines. The numbers in each column on the graph are the means for each group. (D) The percentage of inhibition in 40-fold diluted serum against WT, Delta and Omicron S protein was compared after AZ, Moderna and MVC vaccination. The numbers in each column in Fig. D are the mean subtractions between groups. The results are presented as the means ± SD. p < 0.05 (∗), p < 0.01 (∗∗), p < 0.001 (∗∗∗) and p < 0.0001 (∗∗∗∗).