Fig. 6.

Association of basal immunity and antibody production following vaccination. IFN-γ, TNF-α, and IL-2 secretion from a PBMC culture system was measured by ELISA. Associations between the fold change in antibody titer (A) or neutralization (% of inhibition) (B) following AZ, Moderna, and MVC vaccination and the levels of IFN-γ, TNF-α, IL-2, and the sum of three cytokines before vaccination were calculated using Spearman rank correlation. Lines in the graph are displayed as trend lines. Groups with significant trends are shown in red.