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. 2023 Apr 3;133(7):e165904. doi: 10.1172/JCI165904

Figure 2. Host gene expression classifier for LRTI diagnosis.

Figure 2

(A) Receiver operating characteristic (ROC) curve of the host gene expression classifier in each of the test folds. The median and range of the area under the curve (AUC) are indicated. (B) The number and percentage of patients in the Definite and No Evidence groups who were classified according to their clinical adjudication using a 50% out-of-fold probability threshold. (C) Heatmap showing standardized variance-stabilized expression values across all patients (columns) for the 14 final classifier genes (rows) selected from the full Definite and No Evidence data set. Shown are the LRTI adjudication (top colored horizontal bar) and out-of-fold LRTI probability (top dot plot) of each patient and the regression coefficient of each selected gene (side bar plot).