Table 1.
Demographics and LN class of 72 patients with incident lupus nephritis, Olmsted County, MN (1976–2009) and eight-county region (2010–2018) in southeast Minnesota
| 1976 to 1989 N=10 |
1990 to 1999 N=8 |
2000 to 2009 N=16 |
2010 to 2018 N=38 |
1976-2018 N=72 |
|
|---|---|---|---|---|---|
| Age, years, mean (SD) | 36.6 (16.6) | 29.4 (15) | 37.7 (13.23) | 41.1 (17.31) | 38.4 (16.24) |
| Female sex, n (%) | 9 (90) | 8 (100) | 12 (75) | 26 (68) | 55 (76) |
| Race/Ethnicity*, n (%) | |||||
| Non-Hispanic Asian | 0 (0) | 2 (25) | 5 (31) | 4 (11) | 11 (15) |
| Non-Hispanic Black | 0 (0) | 0 (0) | 1 (6) | 3 (8) | 4 (6) |
| Non-Hispanic White | 10 (100) | 6 (75) | 9 (57) | 25 (66) | 50 (69) |
| Hispanic | 0 (0) | 0 (0) | 1 (6) | 6 (16) | 7 (10) |
| LN Class**, n (%) | |||||
| Class II | 1 (17) | 0 (0) | 1 (7) | 5 (19) | 7 (14) |
| Class III | 1 (17) | 0 (0) | 4 (29) | 4 (15) | 9 (18) |
| Class IV | 2 (33) | 3 (75) | 5 (36) | 10 (37) | 20 (39) |
| Class V | 1 (17) | 1 (25) | 4 (29) | 3 (11) | 9 (18) |
| Class III +V | 0 (0) | 0 (0.0) | 0 (0) | 1 (4) | 1 (2) |
| Class IV + V | 1 (17) | 0 (0.0) | 0 (0) | 4 (15) | 5 (10) |
| No biopsy | 4 (40) | 4 (50) | 2 (13) | 11 (29) | 21 (29) |
*
Cases were assigned to one of the five mutually exclusive race/ethnicity groups based on the self-reported information in the medical records: Hispanic (any race), Asian, White, Black, Other. There were no patients of Other races/ethnicity reported.
**
LN class information was reported according to the 2018 revised International Society of Nephrology/Renal Pathology Society (ISN/RPS) classification criteria for LN.
Abbreviations: ESRD End-stage renal disease.