TABLE 1.
Demographic (Age, Sex) And Clinical (Age of Onset, Illness Duration, Medication Users During Cognitive-Behavioral Therapy (CBT) Trial, Comorbidities, Baseline Children’s Yale-Brown Obsessive Compulsive Scale (CY-BOCS) Severity, Post-CBT CY-BOCS, % of Patients With Positive Response) Data From Pediatric Samples
| Pediatric sample | Adult sample | |||
|---|---|---|---|---|
| HC | OCD | HC | OCD | |
| Male subjects (%) | 49.3 | 55.4 | 42.8 | 49.4 |
| Age, years (mean ± SD) | 13.41 ± 2.74 | 13.10 ± 2.81 | 30.5 ± 9.55 | 31.63 ± 9.65 |
| OCD | OCD | |||
| Age of onset, years (mean ± SD) | 10.43 ± 3.39 | 16.5 ± 8.60 | ||
| Illness duration, years (mean ± SD) | 3.10 ± 2.54 | 15.5 ± 10.85 | ||
| Dimensions, yes (%) | ||||
| Agg. and check | 68.5 | 75.7 | ||
| Cleaning | 64.3 | 67.3 | ||
| Sex. and rel. | 29.2 | 50.3 | ||
| Hoarding | 31.5 | 26.4 | ||
| Ordering | 64.9 | 57.9 | ||
| Medication us at MRI time, yes (%) | 20.8 | 65.7 | ||
| Medication us during CBT, yes (%) | 30.4 | 66.7 | ||
| SSRI | 25.6 | SSRI | 37.7 | |
| Combination | 1.2 | Tricyclics | 2.8 | |
| Other | 3.6 | Combination | 15.1 | |
| Other | 20.4 | |||
| Comorbidities, yes (%) | ||||
| Hx. of anxiety | 30.4 | 31.8 | ||
| Hx. of depression | 6.5 | 36.5 | ||
| Cur. anxiety | 42.3 | 30.2 | ||
| Cur. depression | 7.7 | 23 | ||
| Baseline C/YBOCS severity (mean ± SD) | 24.83 ± 5.21 | 26.29 ± 4.58 | ||
| Post-CBT C/YBOCS severity (mean ± SD) | 14.32 ± 8.67 | 15.45 ± 6.96 | ||
| % C/YBOCS reduction (mean ± SD) / % Patients with positive response | 43.19 ± 32.43/ 56.5 | 40.79 ± 25.29/ 61.6 | ||
Note: Agg and check = Aggressive and checking; Cur = current; Hx = history; OCD = obsessive-compulsive disorder; MRI = magnetic resonance imaging; Sex and rel = sexual and religious; SSRI = selective serotonin reuptake inhibitors.