Table 1.

Study eligibility criteria, by participant type.

Type	Eligibility criteria
Patients in the trial (N = 680)	Inclusion: age ≥ 18 years old; living with HIV infection; receiving HIV care at study site; ≥ 6 months since ART initiation; hazardous alcohol use plus at least one MH/SU comorbidity or moderate/severe AUD; suboptimal HIV care outcome in past year including late (14+ days) ART drug pickup, HIV VL greater than the lower limit of assay detection, or referral to the ART clinic’s enhanced adherence counseling program Exclusion: plan to relocate out of Lusaka in next 6 months; no access to a telephone; actively suicidal and in need of immediate care; alcohol intoxication or withdrawal requiring immediate care; currently psychotic; participating in another study that would interfere with participation
HIV peer counselors providing trial interventions (N = 20)	Inclusion: age ≥ 18 years old, trained in alcohol BI and/or CETA; experience providing trial interventions including having provided alcohol BI to ≥ 10 participants or xpovided CETA to ≥ 5 participants Exclusion: none
HIV clinic staff (N = 20)	Inclusion: age ≥ 18 years old, working for the Ministry of Health; professional or lay non-study health worker; worked at study site for ≥6 months during implementation of the trial Exclusion: none
Key informants (N = 15)	Inclusion: age ≥ 18 years old, clinic/hospital administrator, program manager, policymaker, or other thought leader in areas of HIV, SU, or MH in Zambia Exclusion: none

Abbreviations: HIV, human immunodeficiency virus; MH, mental health; SU, substance use; AUD, alcohol use disorder; ART, antiretroviral therapy; CETA, Common Elements Treatment Approach; BI, brief intervention; VL, viral load.