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. Author manuscript; available in PMC: 2024 Oct 1.
Published in final edited form as: Transl Stroke Res. 2022 Oct 1;14(5):766–775. doi: 10.1007/s12975-022-01093-6

Figure 4. GPR39 KO decreases survival and motor function 1 week after stroke, and increases brain atrophy 3 weeks after stroke.

Figure 4.

A. Timeline of behavior testing, MCAO, infarct size and brain atrophy measurement, superimposed on survival curve. GPR39 KO decreased survival at 1 week compared to WT (*p<0.05). B. Ipsilateral atrophy in cortex, caudate putamen (CP) and hemisphere in KO and WT mice at 3 weeks after stroke. C. KO mice show greater forepaw disability in the Cylinder test 1 week after stroke. Higher asymmetry indicates greater disability. D. KO mice show decreased coordination in the Pole test 1 week after stroke. Longer time indicates greater disability. Total number of KO and WT mice at beginning of protocol was 24 and 21, respectively. Number of mice at full survival to 21 days was 17 in each group (*P <0.05).