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. Author manuscript; available in PMC: 2023 Dec 1.
Published in final edited form as: J Immunol. 2022 Dec 1;209(11):2149–2159. doi: 10.4049/jimmunol.2200324

FIGURE 1. Reduced antitumor immunity in TriVax-immunized microbially experienced cohoused (CoH) mice.

FIGURE 1.

A. Experimental Design – SPF and CoH B6 mice were immunized with OVA257/OVA323-TriVax. After 28 days, mice were challenged with B16-ova cells (2.5 × 105 cells in 0.1 ml s.c.). B. Tumor growth was then monitored over the next 28 days. As a reference, cohorts of unimmunized SPF and CoH mice were also challenged with B16-ova cells. Data in B are representative of 2 replicate experiments. n = 8 mice/group.