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. Author manuscript; available in PMC: 2023 Dec 1.
Published in final edited form as: J Immunol. 2022 Dec 1;209(11):2149–2159. doi: 10.4049/jimmunol.2200324

FIGURE 8. Administration of recombinant IL-27p28:EBI3 complex boosts CD8 and CD4 T cell expansion in TriVax-immunized CoH mice.

FIGURE 8.

A. Experimental design – SPF and CoH B6 mice were immunized with B8R/2W1S-TriVax. Some of the CoH mice then received a single dose (250 μg i.v.) of recombinant IL-27p28:EBI3 complex 2 h later. After 5 days, spleens were collected to quantitate the frequency and number of (B-D) B8R-specific CD8 and (E-G) 2W1S-specific CD4 T cells. * p ≤ 0.05. Data are representative from 2 technical replicates, with a total of 4–5 mice/group.