Table 1.

Study characteristics

	Study	Numbers treated surgically/medically	Year	Study period	Gender (M/F)	Mean age ± S.D [median/IQR]
1	Xiao et al. [41]	(12/3)	2020	Mar 1983–Sep 2018	(8/8)	39/N.S
2	Yalav et al. [38]	(11/0)	2020	2010–2019	(5/6)	44.2 ± 15.8
3	Zenzri et al. [36]	(30/0)	2020	Feb 2000–Nov 2019	(2/28)	[35/18–80]
4	Turner et al. [28]	(25/0)	2019	Aug 2004–Sep 2015	(14/39)	42/N.S
5	Netto et al. [35]	(28/5)	2018	1982–2014	(3/24)	34/19–88
6	Walter et al. [42]	(36/13)	2017	1965–2013	(11/20)	[25/13–76]
7	Burtenshaw et al. [7]	(70/0)	2016	1980–2012	(20/47)	[36/14–83]
8	Mussi et al. [6]	(30/0)	2016	Jan 2000–Sep 2013	(5/28)	[37/28–61]
9	Quast et al. [43]	(0/134)	2016	2003–2015	44/90	35.54 ± 13.7
10	Cates [31]	(29/4)	2015	1983–2011	(13/16)	33.8 ± 24.3
11	Desurmont et al. [34]	(17/80)	2015	1970–2010	(34/45)	33.4 ± 13.05
12	Wilkinson et al. [15]	(50/0)	2014	1998–2013	(2/48)	[36/15–64]
13	Yabanoglu et al. [29]	(13/0)	2014	1997–2013	(2/11)	36 ± 14
14	Bonvalot et al. [16]	(43/4)	2013	1993–2012	(1/40)	[34/18–74]
15	Crago et al. [40]	(171/0)	2013	1982–2011	(166/329)	N.S
16	Wheeler et al. [44]	(18/0)	2012	Not specified	N.S	N.S
17	Wilkinson et al. [33]	(15/0)	2012	2001–2011	(6/9)	[42/19–64]
18	Pencavel et al. [39]	(30/0)	2010	2000–2009	(2/28)	[35]
19	Bertani et al. [20]	(14/0)	2009	Oct 1999–Jun 2008	(3/11)	41.5/16–57
20	Kumar et al. [37]	(30/0)	2009	1995–2004	(10/22)	N.S
21	Lahat et al. [45]	(16/0)	2009	1995–2009	(4/12)	40.5/24–70
22	Smith et al. [30]	(20/0)	2000	Jul 1982–Jun 1998	(12/12)	[39/18–73]
23	Stojadinovic et al. [32]	(41/0)	2001	Jul 1982–Aug 1999	(5/34)	[34/23–79]
				Range 1970–2019	(372/907)	37.9 [35.3]

N.S not specified