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. 2023 Feb 22;70(3):301–312. doi: 10.1007/s12630-022-02393-z
The renouncement of N2O as a carrier gas allows for safely performing low-, minimal-, and metabolic flow anesthesia. This enables significant savings of inhalational anesthetics and better conditioning of inspired gases compared with high-flow anesthesia, which is required during the wash-in and wash-out periods if N2O is used as a carrier gas. Additionally, the negative impact of N2O on CO2e emissions and ozone depletion can be prevented.