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. 2023 Mar 31;13:5280. doi: 10.1038/s41598-023-32433-7

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Network analysis of phosphoproteomics (A) and proteomics (B) of insulin-stimulated adipose tissue reveals the main role of Akt signaling following peripartum dietary ALA supplementation in postpartum dairy cows. Dairy cows were fed; (i) CTL—encapsulated saturated fat, (ii) ALA—flaxseed supplement providing α-linolenic acid (ALA). n = 5 per treatment. The upregulated phosphopeptides or proteins are represented in red, whereas green indicates downregulation. Full lines represent direct interaction, whereas dotted lines represent indirect interaction.