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. 2023 Mar 31;13:5246. doi: 10.1038/s41598-023-32302-3

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Correlations between CSF GOT1 levels and high ICP, brain ischemia, and clinical outcome. CSF GOT1 levels on days 0–3, 5–7, and 14 post-SAH, in association with the presence of increased intracranial pressure (ICP) (A), and at days 5–7 post-SAH with the presence of brain ischemia (hypodense lesion on a brain CT) (B). Correlation between CSF GOT1 levels at days 0–3, 5–7, and 14 post-SAH and outcome defined as “good” (GOS IV–V) versus “poor” (GOS I–III) 3 months post-SAH (C), hospital length of stay (LOS) (D), and the presence of neurological deficits at discharge (E). Data are expressed as the median and interquartile range. Statistical analysis was performed using the Mann–Whitney test (B), *p < 0.05, **p < 0.01.