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. 2023 Mar 31;13:5271. doi: 10.1038/s41598-023-31616-6

Table 3.

Statistics of the Schiff sensitivity score and post-hoc analysis of the mixed effect model for repeated data [mixed effect model; LS mean and 95% CI].

Schiff sensitivity score Adjusted (LS) mean (95% C.I.) Bonferroni post hoc (p-value)
Group N Group SC Group TP Group Time
TP vs N SC vs N TP vs SC 0 vs 2 2 vs 4 0 vs 4
Air  Base

2.04

(1.91, 2.17)

1.96

(1.82, 2.10)

1.97

(1.84, 2.10)

0.0002 0.0901 0.2503  < .0001  < .0001  < .0001
 2w

1.46

(1.32, 1.59)

1.19

(1.05, 1.33)

1.10

(0.97, 1.23)

 4w

1.05

(0.92, 1.19)

0.88

(0.74, 1.02)

0.57

(0.44, 0.70)

Cold  Base

1.87

(1.72, 2.03)

1.96

(1.79, 2.12)

1.96

(1.80, 2.12)

0.0205 0.4782 0.6944  < .0001  < .0001  < .0001
 2w

1.83

(1.68, 1.99)

1.51

(1.35, 1.68)

1.45

(1.30, 1.61)

 4w

1.34

(1.18, 1.50)

1.20

(1.03, 1.36)

0.87

(0.71, 1.03)

Acid  Base

0.23

(0.16, 0.30)

0.16

(0.09, 0.24)

0.25

(0.18, 0.32)

1.0000 1.0000 1.0000 0.0199  < .0001  < .0001
 2w

0.16

(0.09, 0.23)

0.16

(0.08, 0.23)

0.15

(0.08, 0.22)

 4w

0.04

(-0.03, 0.12)

0.05

(-0.03, 0.12)

0.06

(-0.01, 0.13)

VAS  Base

4.05

(3.78, 4.31)

4.29

(4.01, 4.57)

3.75

(3.48, 4.01)

0.0476 1.0000 0.0123  < .0001  < .0001  < .0001
 2w

3.51

(3.25, 3.77)

3.72

(3.44, 4.00)

3.17

(2.91, 3.44)

 4w

3.13

(2.86, 3.39)

3.01

(2.73, 3.29)

2.48

(2.21, 2.74)

LS, least squares; CI, confidence interval; VAS, visual analog scale.

Bold values mean statistical significance.