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. 2023 Mar 31;13:5273. doi: 10.1038/s41598-023-32507-6

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© The Author(s) 2023, corrected publication 2023

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Immunotherapy can affect the number of CD4+ T cells and the ratio of CD4+/CD8+ cells in the peripheral blood of AR mice. Flow cytometry was used to determine the number of CD4+ and CD8+ T cells in the peripheral blood of mice in each group (b). The circle-gate strategy is shown in Figure (a). (c) is the percentage of CD4+ T and CD8+ T cells in peripheral blood, and d is the ratio of CD4+ to CD8+ cells in each group. *P < 0.05, **P < 0.01.