Table 1.
Penicillin susceptibility profile among meningeal and non-meningeal S. pneumoniae strains in children under 5 years in Brazil, 2006-2021. Prevalence of highly resistant serotype 19A (ST19A) is provided (adapted from reference70).
| Year | MENINGITIS STRAINS |
NON-MENINGITIS STRAINS |
ST19A | |||||
|---|---|---|---|---|---|---|---|---|
| Non-susceptible | Susceptible | n | Non-susceptible | Intermediate resistance | Susceptible | n | N (%) | |
| 2006 | 45.0% | 55.0% | 222 | 32.8% | 32.8% | 34.3% | 64 | 11 (3.8%) |
| 2007 | 48.6% | 51.4% | 220 | 0.0% | 17.9% | 82.1% | 75 | 8 (2.5%) |
| 2008 | 48.3% | 51.7% | 145 | 0.0% | 14.9% | 85.1% | 154 | 15 (5.0%) |
| 2009 | 46.5% | 53.5% | 129 | 0.0% | 18.8% | 81.2% | 69 | 6 (3.0%) |
| 2010 | 53.6% | 46.4% | 140 | 0.0% | 17.3% | 82.7% | 75 | 13 (6.0%) |
| 2011 | 35.7% | 64.3% | 126 | 0.0% | 9.7% | 90.3% | 93 | 16 (7.3%) |
| 2012 | 36.3% | 63.7% | 91 | 0.0% | 7.5% | 92.5% | 106 | 19 (9.6%) |
| 2013 | 32.3% | 67.7% | 62 | 0.0% | 10.9% | 89.1% | 92 | 19 (12.3%) |
| 2014 | 38.6% | 61.4% | 57 | 0.0% | 18.6% | 81.4% | 87 | 37 (28.2%) |
| 2015 | 40.0% | 60.0% | 55 | 0.0% | 20.0% | 80.0% | 85 | 40 (28.6%) |
| 2016 | 32.3% | 67.7% | 62 | 0.0% | 16.1% | 83.9% | 88 | 47 (31.3%) |
| 2017 | 48.0% | 52.0% | 58 | 0.0% | 9.0% | 91.0% | 91 | 48 (32.2%) |
| 2018 | 45.6% | 54.4% | 57 | 0.0% | 23.1% | 76.9% | 117 | 70 (40.2%) |
| 2019 | 65.0% | 35.0% | 80 | 1.1% | 28.7% | 70.2% | 94 | 78 (44.6%) |
| 2020 | 66.7% | 33.3% | 12 | 0.0% | 28.9% | 71.1% | 47 | 20 (33.9%) |
| 2021 | 66.7% | 33.3% | 29 | 0.0% | 28.9% | 71.1% | 79 | 41 (38.0%) |