Table 2.

Perceived use of clinical PRS

Themes/Subthemes	Example Quotes
Personal health benefits	“I’m already grabbing the bull by the horns and I’d say, if I’m already aware of this I’m going to start taking preventive measures, that I’ll do this and that and start with my home remedies.” (P31, Sp-speaking)
Prioritized the utility of PRS-related information by disease type	“It’s good, for example, for a person that doesn’t have cholesterol that test would be very useful, but for someone like me, who already has it, we wouldn’t understand if this result would be good or bad.” (P39, Sp-speaking)
Personal initiative	“No, it depends on the person and their attitude, and how much the person love life, how much the person knows about their body and love themselves and their body. It depends on a person.” (P10, Eng-speaking)
Adequate understanding of next steps	“Well not knowing what steps to take, what you have to do to resolve the situation…” (P18, Sp-speaking)
No additional gain to personal health	“I think I would want to know more if I were diabetic, if I were healthy, if I were a fit gym rat, I probably wouldn’t concern myself that much with it.” (P12, Eng-speaking)
Person’s age may influence utility	“People now in this day in time, my people that I know, my age, they’re enjoying life now to the fullest. They’re not thinking about, ‘What if I have this or that?’” (P10, Eng-speaking)
Family health benefits	“I think my husband would agree, and my children would agree too. It would be good to know, it would be a warning to them about the risks.” (P23, Sp-speaking)
Community health benefits	“I feel with the risk scores…you guys could find out more or less on how a disease, how does it affect one race compared to another” (P09, Eng-speaking)

Eng, English; PRS, polygenic risk score; Sp, Spanish.