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Elexacaftor/tezacaftor/ivacaftor decreases interleukin (IL)-6 production by lipopolysaccharide (LPS)-treated cells. IL-6 in supernatants of cystic fibrosis peripheral blood mononuclear cells (PBMCs) before (Pre) and after 1 month of treatment (M1) at baseline (untreated) and after LPS induction. Two-way ANOVA with Bonferroni multiple comparison test. **: p<0.01; ****: p<0.0001.
