Table 1 .
Breast cancer liver metastases status for surgical group
| Study | Total no. of patients | Single metastases (%) | Synchronous metastases (%) | Mean age at hepatectomy ± sd | Resection margins | Receptor status | Extrahepatic disease (%) | |||
|---|---|---|---|---|---|---|---|---|---|---|
| R0 | R1/2 | ER+ | PR+ | HER+ | ||||||
| Chun10 | 136 | – | 56 (41) | – | – | – | 88 (65) | 51 (38) | 47 (36) | 31 (23) |
| Feng11 | 65 | 42 (65) | – | 51±11 | 62 (95) | 3 (5) | – | – | 32 (49) | 50 (77) |
| He12 | 67 | 43 (64) | 1 (1) | 51±11 | 64 (96) | 3 (4) | – | – | 14 (21) | 14 (21) |
| Lucidi13 | 72 | 33 (46) | 21 (29) | – | – | – | 57(79) | 45(63) | 32(40) | 21 (29) |
| Sundén14 | 29 | 19 (66) | – | 54 | 17 (59) | 6 (21) | 13 (59) | 9 (45) | 9 (45) | – |
| Cheung15 | 21 | – | – | 45 | 21 (100) | – | 11 (52) | 8 (38) | 5 (24) | – |
| Bacalbasa16 | 67 | 33 (49) | 54 (81) | – | 62 (93) | 5 (7) | 31(46) | 30(45) | 1(1) | – |
| Labgaa17 | 59 | 31 (62) | 6 (11) | 58 | 36 (71) | 15 (30) | – | – | – | 24 (41) |
| Ruiz18 | 139 | – | 11 (8) | – | 77 (55) | 51 (37) | 74 (53) | 40 (29) | 35(25) | 67 (48) |
| Ruiz19 | 139 | 56 (41) | – | 49±11 | – | – | 55 (82) | 41 (65) | 17 (34) | – |
| Abbas20 | 23 | 15 (65) | 8 (35) | 54 | 16 (73) | – | 17 (94) | 9 (50) | 5 (28) | 4 (17) |
| Ruiz21 | 139 | 56 (40) | 11 (8) | 51±11 | 77 (55) | 51 (37) | 74 (53) | 39 (28) | 35 (25) | 41 (29) |
| Margonis22 | 131 | – | – | 54±14 | 108 (90) | 11 (10) | 66 (73) | 53 (59) | 54 (54) | 15 (13) |
| Sadot23 | 69 | 44 (64) | 7 (10) | 51±11 | 43 (84) | – | 42 (78) | 32 (59) | 29 (45) | – |
| Bacalbasa24 | 43 | 24 (56) | 4 (9) | 53±11 | 39 (91) | 4 (91) | 22 (82) | 22 (82) | 27 (62) | – |
| Sabol25 | 15 | 9 (60) | 1 (6) | 49±9 | 15 (100) | 0 (0) | 8 (53) | 6 (40) | 4 (26) | 3 (20) |
| Kim26 | 13 | 7 (54) | 2 (15) | 51±9 | – | – | 7 (54) | 7 (54) | 5 (38) | 6 (46) |
| Mariani27 | 100 | 65 (65) | 7 (7) | 50±7 | 82 (82) | 18 (18) | – | – | 12 (12) | 22 (22) |
| Kostov28 | 42 | 22 (52) | – | – | 35 (83) | 7 (17) | 19 (45) | 4 (9) | 9 (21) | 20 (47) |
| Dittmar29 | 34 | 12 (35) | 6 (17) | – | 21 (61) | 13 (39) | – | – | 22 (64) | 12 (35) |
| Polistina30 | 12 | 12 (100) | – | 60±10 | 11 (91) | 1 (9) | 9 (75) | 5 (41) | – | – |
| van Walsum31 | 32 | 22 (68) | 6 (18) | 50±6 | 29 (90) | 3 (10) | 20 (62) | – | 8 (25) | 28 (87) |
| Groeschl32 | 115 | – | 24 (20) | – | 92 (80) | 23 (20) | – | – | – | – |
| Abbott33 | 86 | 53 (62) | 25 (29) | – | 77 (90) | 9 (10) | 59 (69) | 59 (69) | 32 (37) | 24 (27) |
| Duan34 | 16 | – | – | – | – | – | – | – | – | – |
| Rubino35 | 18 | 10 (55) | 1 (5) | 46±7 | 18 (100) | 0 (0) | 12 (66) | 12 (66) | 4 (22) | 0 (0) |
| Hoffmann36 | 41 | 20 (49) | 4 (10) | – | 32 (78) | 9 (22) | 18 (44) | 14 (34) | 11 (26) | 12 (30) |
| Caralt37 | 12 | – | 2 (16) | 57±11 | 9 (75) | 3 (25) | 9 (75) | 9 (75) | – | 1 (8) |
| Lubrano38 | 16 | 12 (75) | 0 (0) | 53±7 | 16 (100) | 0 (0) | 10 (83) | 8 (66) | – | 0 (0) |
| Thelen39 | 39 | 20 (51) | 6 (15) | – | 28 (72) | 11 (28) | 26 (66) | 19 (48) | 14 (35) | 13 (33) |
| Adam40 | 85 | 32 (37) | 9 (11) | 47±8 | 56 (66) | 29 (34) | 44 (51) | 21 (24) | 24 (28) | 27 (31) |
| Sakamoto41 | 34 | 19 (56) | 4 (11) | 51±8 | – | – | 17 (50) | – | – | 9 (26) |
| Vlastos42 | 31 | 20 (64) | 9 (29) | 46±7 | – | – | 18 (53) | 11 (35) | – | 0 (0) |
| Elias43 | 54 | – | 12 (22) | 49±5 | 44 (81) | 10 (19) | 32 (59) | 32 (59) | – | 0 (0) |
| Selzner44 | 17 | 12 (71) | – | 49±12 | 17 (100) | 0 (0) | 3 (17) | – | – | 3 (17) |
| Pocard45 | 52 | 36 (69) | – | 47±9 | 51 (98) | 1 (2) | 19 (67) | – | – | 11 (23) |