Table 1:
Participant demographics
CF (n=56) | Non-CF (n=92) | P value | |
---|---|---|---|
Age (years) | 28.6 ± 13.4 | 37.0 ± 9.8 | 0.0001 |
Female | 41.1% | 51.1% | 0.24 |
Caucasian | 94.6% | 91.3% | 0.46 |
CFTR genotype | |||
Homozygous F508del (n=26) | 46.4% | --- | |
Heterozygous F508del (n=29) | 51.2% | --- | |
Baseline BMI (mean) | 22.6 ± 4.7 | --- | |
Prior CFTR modulator | 50.0% | ||
Baseline FEV1 (% predicted) | 65.5 ± 25.3 | --- | |
Hospitalizations 1 year prior to ETI initiation | 0.6 ± 1.4 | --- | |
Oral antibiotic courses 1 year prior to ETI initiation | 2.4 ± 2.3 | --- |
P values determined by unpaired t-test for continuous variables or Fisher’s Exact test for categorical variables.