Table 4.
Device | Detection principle | Target | Limit of detection | Time (min) | References |
---|---|---|---|---|---|
Dengue fever | |||||
NAAT | QUASR multiplexed RT-LAMP assay | RNA | 108–103 pfu/mL | < 40 min | [164] |
IoT PCR | PCR | cDNA | – | 34 min | [165] |
Influenza A | |||||
Fluorescent probe based POC | Fluorescence and light guiding | H1N1 | 138 pg/mL | 40 min | [126] |
Genosensor | Electrochemical | Hemagglutinin gene | 0.002 ng/6 μL | 30 min | [166] |
Human immunodeficiency virus | |||||
EGOFET | Electrochemical | HIV-1 p24 capsid protein | 1 fM | – | [167] |
Coronavirus-2 | |||||
Supersandwich-type biosensor | Electrochemical | SARS-CoV-2 RNA | 200 copies/mL | – | [168] |
Liquid crystal film | Thermotropic Liquid | RNA-CoV2 | fM | 20 min | [169] |
Sensors | Localized Surface Plasmon Resonance | SARS-CoV-2 virus particle | 125.28 vp/mL | ||
Others | |||||
Plasmon resonance probes | Dark-field microscope | Enterovirus A71 | 3 copies/μL | [132] | |
Immunochromatographic strip | LFA | EBOV-GP1−649 | 200 ng/mL | 15 min | [170] |
Impedimetric micro-immunosensor | Electrochemical | ZIKV protein | 10 pM | 40 min | [171] |
cDNA Complementary deoxyribonucleic acid, NAAT Nucleic acid amplification tests, QUASR Quenching of unincorporated amplification signal reporters, EGOFET Electrolyte-gated organic field-effect transistor, ELISA Enzyme-linked immunosorbent assay, LAMP Loop-mediated isothermal amplification, LFA Lateral flow assay, LFD Lateral flow dipstick, MCFA Microchannel capillary flow assay, RNA Ribonucleic acid, RPA Recombinase polymerase amplification, RT-LAMP Reverse transcription loop-mediated isothermal amplification, SARS Severe acute respiratory syndrome