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. 2023 Mar 3;15(3):e35735. doi: 10.7759/cureus.35735

Table 2. Clinicopathological predictors of IC in patients with a preoperative diagnosis of DCIS.

DCIS = ductal carcinoma in situ; IC = invasive carcinoma; OR = odds ratio; CI = confidence interval

Variable Risk for invasive carcinoma
  Univariate analysis Multivariate analysis
OR (95% CI) P-value Adjusted OR (95% CI) P-value
Age
>50 1.411 (0.59-3.38) 0.439    
Ultrasound findings
Mass lesion 1.06 (0.31-3.62) 0.92    
Size on the mammogram
>20 mm 1.94 (0.52-7.16) 0.321    
Mammogram findings
Microcalcification 0.5 (0.15-1.65) 0.252 0.58 (0.169-2.03) 0.397
Multifocality
Yes 3.54 (1.32-9.5) 0.012 3.011 (1.037-8.74) 0.043
Presentation
Symptomatic 1.67 (0.74-3.78) 0.214    
Grade
High 1.17 (0.42-3.22) 0.766    
Necrosis
Yes 1.71 (0.77-3.82) 0.19 2.037 (0.874-4.75) 0.099