TABLE 1.
Comparison of clinical features between AML‐MRC‐C, AML‐MRC‐H, and AML‐MRC‐M
| Clinical feature | Total (n = 266) | AML‐MRC‐C (n = 142) | AML‐MRC‐H (n = 99) | AML‐MRC‐M (n = 25) | p‐value |
|---|---|---|---|---|---|
| Age (y), median [range] | 70 [18–91] | 70 [30–91] | 70 [19–89] | 73 [18–90] | 0.475 a |
| Male, n (%) | 168 (63) | 86 (61) | 64 (65) | 18 (72) | 0.510 b |
| WBC count ×109/L, median [range] | 3.4 [0.1–328.7] | 3.4 [0.3–292.4] | 3.7 [0.1–328.7] | 3.2 [0.8–60.6] | 0.606 a |
| Platelets ×109/L, median [range] | 47 [3–1057] | 47.5 [7–1057] | 42 [3–703] | 52.5 [14–490] | 0.602 a |
| Hemoglobin, g/dL, median [range] | 85 [8–671] | 85 [8–671] | 87 [57–148] | 82 [55–108] | 0.452 a |
| BM blasts %, median [range] | 39.5 [20–95] | 48 [20–95] | 35 [20–91] | 31 [20–82] | 0.017 a |
| LDH, IU/L, median [range] | 304 [90–9473] | 304 [94–9473] | 305 [101–6550] | 277 [90–1566] | 0.535 a |
| Number of mutated genes, median [range] | 3 [0–9] | 2 [0–8] | 3 [0–9] | 4 [1–7] | <0.0001 a |
| Allo‐HSCT, n (%) | 57 (21) | 30 (21) | 23 (23) | 4 (16) | 0.727 b |
Abbreviations: Allo‐HSCT, allogeneic hematopoietic stem cell transplantation; BM, bone marrow; LDH, lactate dehydrogenase; WBC, white blood cell.
a
Kruskal–Wallis test.
b
Chi‐square test.