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. 2023 Apr 1;15:66. doi: 10.1186/s13098-023-01043-8

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© The Author(s) 2023

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 4 — Distribution of indications in cardiometabolic drug clinical trials

(A) Number of clinical trials according to the indication in cardiometabolic diseases. (B) Trials are divided into monomer drug, chemical polypill, and TCM compound. (C) The number of drug trials for different indications. Blue represents one indication. Green represents two indications. Yellow represents three indications, and red represents four indications. (D) In the chemical polypill, the number of drug trials for different indications. The blue represents one indication which suggested that the polypill for one indication. The green represents two indications for polypill. The yellow represents three indications and the red represents four indications. (E) In TCM compounds, the number of drug trials for different indications. The blue represents one indication and the green represents two indications. Numbers above each column of the chart represent the actual number of trials. Abbreviations: TCM, Traditional Chinese Medicine