FIGURE 4.

Pharmacokinetics of zolbetuximab. Mean zolbetuximab serum levels over time in patients following the first infusion (cycle 1, solid line) or third infusion (cycle 3, dotted line) presented on a semilogarithmic scale for (A) the total zolbetuximab 800/600 mg/m² cohort (Safety Part Arm A + Expansion Part) and (B) the zolbetuximab 1000 mg/m² cohort (Safety Part Arm B). Standard deviation was not calculated since ≥50% of values were below the LLOQ or the number of observations was ≤2 at a given time point. LLOQ, lower limit of quantification.