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. 2022 Dec 26;114(4):1686–1696. doi: 10.1111/cas.15703

FIGURE 4.

FIGURE 4

(A) miR‐192‐5p levels in medium 48 h after cisplatin concentration to KYSE170 cells. The release of miR‐192‐5p to medium increased as the concentration of cisplatin was increased. (B) Comparison of miR‐192‐5p level in plasma between before and after neoadjuvant chemotherapy (NAC). The levels of miR‐192‐5p significantly increased after NAC (p = 0.015). (C) miR‐192‐5p levels in plasma before NAC, after NAC, and after surgery were examined for grades 1 (n = 1) and 3 (n = 1). In the patient with grade 3, the level of miR‐192‐5p was higher in all periods, especially after NAC. Cutoff value of miR‐192‐5p was determined as 3.5 by median value of whole cohort. DCF, docetaxel + cisplatin + 5‐FU.