TABLE 1.
Association between plasma miR‐192‐5p and clinicopathological factors in EC without NAC
| Variables | n = 44 | Plasma miR‐192‐5p before treatment | p‐value a | ||
|---|---|---|---|---|---|
| Low (≤3.5) | High (>3.5) | ||||
| n = 22 | n = 22 | ||||
| Age | >65 | 30 | 13 (43%) | 17 (57%) | 0.195 |
| ≤65 | 14 | 9 (64%) | 5 (36%) | ||
| Sex | Male | 38 | 18 (47%) | 20 (53%) | 0.379 |
| Female | 6 | 4 (67%) | 2 (33%) | ||
| Tumor size (mm) | >40 | 19 | 7 (37%) | 12 (63%) | 0.128 |
| ≤40 | 25 | 15 (60%) | 10 (40%) | ||
| Pathological T factor b | T3,4 | 7 | 1 (5%) | 6 (95%) | 0.039 |
| T1,2 | 37 | 21 (56%) | 16 (44%) | ||
| Pathological N factor b | N1‐4 | 16 | 5 (31%) | 11 (69%) | 0.060 |
| N0 | 28 | 17 (61%) | 11 (39%) | ||
| Lymphatic invasion b | + | 21 | 6 (29%) | 15 (71%) | 0.006 |
| − | 23 | 16 (69%) | 7 (31%) | ||
| Venous invasion b | + | 22 | 4 (18%) | 18 (82%) | <0.001 |
| − | 22 | 18 (82%) | 4 (18%) | ||
| Pathological stage b | 2, 3 | 20 | 6 (30%) | 14 (70%) | 0.015 |
| 1 | 24 | 16 (67%) | 8 (33%) | ||
a
p‐values were calculated using the chi‐squared test.
b
According to the 11th edition of the Japanese Classification of Esophageal Cancer.