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. 2023 Jan 27;14(2):915–929. doi: 10.1002/jcsm.13177

Figure 3.

Figure 3

hucMSCs ameliorate immobilization (IM)‐induced muscle atrophy. (A) Grip strength (n = 5 mice). (B) Running distance evaluated by exhaustive running test (n = 5 mice). (C) Lean mass proportion detected by DXA (n = 5 mice). (D) Percentage of TA muscle weight in body weight (n = 5 mice). (E) H&E staining and immunohistochemical staining of fast and slow myosin heavy chain of TA muscles (scale bar, 50 μm). And cross‐sectional area (CSA) of muscle fibres, fast and slow muscle fibres and the ratio of slow muscle fibres to fast muscle fibres (n = 3–5 mice). (F) Western blot analysis of Atrogin 1 and MuRF1 in TA muscles (n = 3 mice). Quantification of bands was performed using ImageJ software. Data are mean ± SEM. (*P < 0.05, **P < 0.01, ***P < 0.001 by two‐sided unpaired Student's t‐test).