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The agrin pathway. Agrin complex (Agrin, Lrp4, MuSK, Dok7) localization within the neuromuscular junction structure (right panel); agrin complex detailed structure and site of proteolytic cleavage of C‐terminal agrin fragment (CAF) by neurotrypsin (middle panel); schematic representation of agrin cleavage by neurotrypsin and CAF release within the blood circulation (middle and right panels).
