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. 2023 Mar 20;14:1170243. doi: 10.3389/fphar.2023.1170243

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Copyright © 2023 Ding, Liao, Yang, Wei, Xing, Wu, Li, Mao and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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CHR prevents the colocalization of TXNIP and NLRP3 in TGF-β-induced SFs. (A) Confocal microscopic images of treated SFs that were immunostained with anti-TXNIP (red), anti-NLRP3 (green), and DAPI (blue). (B) Double immunofluorescence colocalization of TXNIP and NLRP3 at ×630 magnification. n = 6. Scale bars: 20 μm. The data in this figure are presented as the mean ± standard deviation, and statistical significance was determined with one-way ANOVA followed by Tukey’s post hoc analysis. ∗p < 0.05.