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. 2023 Mar 20;14:1139532. doi: 10.3389/fphar.2023.1139532

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Copyright © 2023 Yang, Liu, Yan and Shang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of frog skin AMPs on lipid metabolism in ox-LDL induced foam cells. Gene expression of membrane proteins involved in ox-LDL uptake and cholesterol efflux by real-time quantitative PCR in foaming THP-1 cells (A,B) and GAPDH was used as an internal reference; Expression of proteins involved in ox-LDL uptake and cholesterol efflux by Western blot in foaming RAW264.7 cells (C–E) and ATP1A1 was used as an internal reference; Flow cytometry analysis of CD36 expression in foaming THP-1 cells (F,G). *p < 0.05 vs. the ctrl group. ^# p < 0.05 vs. the ox-LDL group.