Table 2.

Comparison of technologies and their applications in studies of neurite regeneration and repair

Technologies	Application	Applicable model animal	Advantages	Disadvantages	References
Femtosecond laser surgery	Vaporizing targeted single axon or dendrite branch	C. elegans; Drosophila	Quick, and precise	Relatively expensive	Galbraith and Terasaki 2003; Sugimura et al. 2003; Yanik et al. 2004
Microinjection needle surgery	Mechanical truncation of single dendrite branch	C. elegans	Low cost and convenient	Requires intense training	Zhao et al. 2021
Forceps pinched surgery	Mechanical crushing of neuronal axons	Drosophila	Quick, low cost	Technically challenging	Xiong et al. 2010
Mechanical stress induced spontaneous axonal break	unc-70/β-spectrin mutants are capable of regenerating and repairing axonal breaks	C. elegans	Convenient	Only applies to specific neurons	Nix et al. 2014