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. 2023 Apr 1;13:5341. doi: 10.1038/s41598-023-32291-3

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Approximately 54% of the one-to-one orthologs identified in inter-species ortholog analysis have GO term annotations, which are represented as circles in the figure (see Supplemental Table S10 for detail). Multidimensional scaling (MDS) was used in Revigo to reduce the dimensionality of the matrix for these 38 GO terms based on pairwise similarities in biological function. The size of the circle and color indicates the Log fold change of the ortholog (bacteriocyte compared to body) within a unique GO term category.