Table 1.
Baseline characteristics of the study population.
| Sham (n = 26) | CPAP (n = 26) | p Value | |
|---|---|---|---|
| Age, year | 48.8 ± 10.7 | 49.1 ± 11.4 | 0.920 |
| Male sex, n (%) | 24 (92) | 24 (92) | 1.000 |
| Height, cm | 169.9 ± 7.3 | 170.9 ± 6.8 | 0.583 |
| Weight, kg | 76.2 ± 12.6 | 81.7 ± 11.7 | 0.108 |
| Body mass index, kg/m2 | 26.2 ± 3.0 | 27.8 ± 2.8 | 0.047 |
| Body surface area, m2 | 1.90 ± 0.18 | 1.96 ± 0.18 | 0.234 |
| Systolic BP mmHg | 127.8 ± 16.0 | 126 ± 19.6 | 0.722 |
| Diastolic BP mmHg | 77.3 ± 10.6 | 75.8 ± 13.7 | 0.662 |
| Hypertension, n (%) | 15 (58) | 17 (65) | 0.569 |
| Diabetes mellitus, n (%) | 1 (4) | 4 (15) | 0.158 |
| Dyslipidemia, n (%) | 2 (7) | 8 (31) | 0.035 |
| Current smokers, n (%) | 6 (23) | 10 (39) | 0.229 |
| Medications | |||
| Calcium channel blockers, n (%) | 8 (31) | 10 (39) | 0.560 |
| RAAS blockers, n (%) | 8 (31) | 9 (35) | 0.768 |
| Beta-blockers, n (%) | 4 (15) | 4 (15) | 1.000 |
| Diuretics, n (%) | 0 (0) | 0 (0) | 1.000 |
| Statins, n (%) | 2 (7) | 8 (31) | 0.035 |
| Polysomnographic characteristics | |||
| AHI, events/hour | 53.4 ± 20.5 | 64.2 ± 20.5 | 0.063 |
| Mean oxygen saturation, % | 94.5 ± 1.6 | 93.9 ± 1.7 | 0.238 |
| T90, % | 7.1 ± 7.3 | 10.5 ± 11.6 | 0.210 |
| Average heart rate during sleep, bpm | 62.3 ± 6.3 | 63.3 ± 6.8 | 0.576 |
| Oxygen desaturation index, events/hour | 40.8 ± 20.5 | 47.7 ± 19.6 | 0.239 |
Values are n (%) or mean ± standard deviation.
CPAP continuous positive airway pressure, AHI apnea/hypopnea index, BP blood pressure, RAAS renin–angiotensin–aldosterone system, T90 percentage of sleep time below 90% oxygen saturation.