Table 1.

CRISPR/Cas9 techniques and colon Cancer.

Type	Gene modified	References
knockout	PUM1 and DDX5; WHSC1; AP-2α; CYSLTR1; FGFR1 and OXTR; SASH1; Par3L; caspase-3; NR1H4; uPAR; HNRNPA2B1; GPVI; NSD2; p38γ; CATSPER1; NMRAL2P; HABP4; ZAP and APC; PRDM1; LDHA and LDHB; NAT1; SDHB; VDR; PPIP5KS; NOXO1; PLAUR; PPIP5K; NHLRC2; BrafV600E; LIF; CXCR-4; SGPL1; DACH1; CD133; APC; RNF43; H3K27Ac; GUCY2C; METTL3; CD44 and TLR4; CCAT2; CBS; TGM2; STAT3; mindin; GSTO1 and αIP3/A20; COMP; TRIM11; MBTPS1; RhoB; CD44v6 and YB-1; Crb3; PP2A; Bid; USP29; CD133; Wnt-1; NHE8; P-cadherin; IL-6; SPHK1; IDO-1; ILK; AH1; SIAE; CD133; Nrp2; Tks4; p53 R273H; ALDOB; SNPs	(13–78)
gene editing	Rspo2 and Rspo3; APC, Smad4, Tp53 and KRAS; rs11064124; KRAS, MEK1, PIK3CA and MTOR; TP53; APC; KRAS and TP53; APC; CXCR2 and IL-2; MLH1; β-catenin; IL12 and CXCL11; MUC5AC; VEGF-A; HuR; ERO1α; PC; αTAT1; MARCH2; Klotho; FAPP2; CLCA1; rs4779584 and rs1406389; rs34149860; rs6854845; p53	(77–101)
CRISPR library	HMGCR, FDPS and GGPS1; GRB7; ZEB2; β-catenin; KRAS; CCT6A, RHOQ, RRP12, UTP18, DDOST, YRDC, ACTG1, RFT1 and NLE1; CRS; ERN1; LGALS2; NFKBIZ, ZC3H12A and PIGR;/; TRAF5	(102–113)