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. 2023 Apr 3:1–12. Online ahead of print. doi: 10.1007/s00586-023-07678-5

Table 2.

Functional outcomes between the two groups preoperatively and during the 24-month follow-up period

Full endoscopic (n = 30) Tubular-based microscopic (n = 30) Mean difference (95% CI) adjusted preoperative p-value
Mean ± SD Mean change (95% CI) Mean ± SD Mean change (95% CI)
VAS back pain
Preoperative 7.5 ± 2.49 Reference 6.43 ± 3.04 Reference
1 day 1.5 ± 2.01 − 6 (− 6.89, − 5.11) 1.83 ± 2.17 − 4.6 (− 5.6, − 3.6) − 1.4 (− 2.74, − 0.06) 0.041*
2 weeks 1.7 ± 1.68 − 5.8 (− 6.69, − 4.91) 1.7 ± 1.66 − 4.73 (− 5.74, − 3.73) − 1.07 (− 2.41, 0.28) 0.12
6 weeks 2.07 ± 2.26 − 5.43 (− 6.33, − 4.54) 1.87 ± 2.13 − 4.57 (− 5.57, − 3.56) − 0.87 (− 2.21, 0.48) 0.207
3 months 2.33 ± 2.19 − 5.17 (− 6.06, − 4.27) 2.5 ± 2.52 − 3.93 (− 4.94, − 2.93) − 1.23 (− 2.58, 0.11) 0.072
6 months 1.87 ± 2.32 − 5.63 (− 6.53, − 4.74) 2.8 ± 2.38 − 3.63 (− 4.64, − 2.63) − 2 (− 3.34, − 0.66) 0.004*
12 months 2.1 ± 2.25 − 5.4 (− 6.29, − 4.51) 2.83 ± 2.8 − 3.6 (− 4.6, − 2.6) − 1.8 (− 3.14, − 0.46) 0.009*
24 months 2.19 ± 2 − 5.14 (− 6.08, − 4.21) 2.65 ± 2.45 − 3.66 (− 4.68, − 2.63) − 1.48 (− 2.87, − 0.09) 0.037*
VAS leg
Preoperative 6.83 ± 2.45 Reference 7.5 ± 2.16 Reference
1 day 0.93 ± 1.55 − 5.9 (− 6.6, − 5.2) 0.87 ± 1.76 − 6.63 (− 7.57, − 5.7) 0.73 (− 0.43, 1.9) 0.218
2 weeks 0.27 ± 0.58 − 6.57 (− 7.26, − 5.87) 1.03 ± 1.59 − 6.47 (− 7.4, − 5.53) − 0.1 (− 1.27, 1.07) 0.867
6 weeks 0.3 ± 0.7 − 6.53 (− 7.23, − 5.84) 1 ± 1.44 − 6.5 (− 7.44, − 5.56) − 0.03 (− 1.2, 1.13) 0.955
3 months 0.47 ± 1.2 − 6.37 (− 7.06, − 5.67) 1.53 ± 2.19 − 5.97 (− 6.9, − 5.03) − 0.4 (− 1.57, 0.77) 0.502
6 months 0.57 ± 1.19 − 6.27 (− 6.96, − 5.57) 1.7 ± 2.22 − 5.8 (− 6.74, − 4.86) − 0.47 (− 1.63, 0.7) 0.433
12 months 1.07 ± 1.95 − 5.77 (− 6.46, − 5.07) 2.17 ± 2.63 − 5.33 (− 6.27, − 4.4) − 0.43 (− 1.6, 0.73) 0.467
24 months 1.31 ± 1.67 − 5.56 (− 6.29, − 4.84) 2 ± 2.4 − 5.49 (− 6.46, − 4.53) − 0.07 (− 1.28, 1.14) 0.905
ODI
Preoperative 43.29 ± 15.8 Reference 45.1 ± 18.92 Reference
1 day 15.1 ± 10.58 − 28.19 (− 33.07, − 23.31) 19.23 ± 13.49 − 25.87 (− 32, − 19.73) − 2.32 (− 10.16, 5.52) 0.562
2 weeks 16.09 ± 12.19 − 27.21 (− 32.09, − 22.32) 13.14 ± 11.83 − 31.96 (− 38.1, − 25.83) 4.76 (− 3.08, 12.6) 0.234
6 weeks 13.15 ± 12.58 − 30.14 (− 35.03, − 25.26) 13.93 ± 9.85 − 31.16 (− 37.3, − 25.03) 1.02 (− 6.82, 8.86) 0.799
3 months 9.41 ± 9.63 − 33.88 (− 38.77, − 29) 13.06 ± 14.03 − 32.04 (− 38.17, − 25.9) − 1.85 (− 9.69, 5.99) 0.644
6 months 6.74 ± 7.97 − 36.55 (− 41.43, − 31.67) 13.15 ± 16.1 − 31.95 (− 38.08, − 25.81) − 4.61 (− 12.45, 3.23) 0.25
12 months 9.13 ± 10.06 − 34.16 (− 39.04, − 29.28) 13.57 ± 15.75 − 31.53 (− 37.67, − 25.39) − 2.63 (− 10.47, 5.21) 0.511
24 months 9.48 ± 10.05 − 33.62 (− 38.58, − 28.66) 11.53 ± 13.21 − 32.3 (− 38.57, − 26.04) − 1.31 (− 9.3, 6.68) 0.748
EQ-5D
Preoperative 0.419 ± 0.2107 Reference 0.3191 ± 0.2926 Reference
2 weeks 0.8771 ± 0.0836 0.46 (0.38, 0.54) 0.7887 ± 0.1853 0.47 (0.38, 0.56) − 0.01 (− 0.13, 0.11) 0.85
6 weeks 0.8526 ± 0.2128 0.43 (0.35, 0.51) 0.823 ± 0.1433 0.5 (0.42, 0.59) − 0.07 (− 0.19, 0.05) 0.246
3 months 0.8722 ± 0.1868 0.45 (0.37, 0.53) 0.8145 ± 0.1795 0.5 (0.41, 0.58) − 0.04 (− 0.16, 0.08) 0.486
6 months 0.887 ± 0.1665 0.47 (0.39, 0.55) 0.8477 ± 0.1591 0.53 (0.44, 0.62) − 0.06 (− 0.18, 0.06) 0.318
12 months 0.8223 ± 0.2277 0.4 (0.32, 0.48) 0.8331 ± 0.209 0.51 (0.43, 0.6) − 0.11 (− 0.23, 0.01) 0.068
24 months 0.91 ± 0.1 0.48 (0.4, 0.56) 0.86 ± 0.12 0.53 (0.44, 0.62) − 0.05 (− 0.16, 0.07) 0.451
Walking time
Preoperative 9.56 ± 15.91 Reference 15.5 ± 15.63 Reference
2 weeks 32.17 ± 26.8 22.6 (12.32, 32.89) 33.77 ± 27.47 18.27 (7.52, 29.02) 4.34 (− 10.54, 19.21) 0.568
6 weeks 49 ± 29.78 39.44 (29.15, 49.72) 42.5 ± 30.79 27 (16.25, 37.75) 12.44 (− 2.44, 27.31) 0.101
3 months 54.83 ± 30.98 45.27 (34.99, 55.55) 47.33 ± 34.36 31.83 (21.08, 42.58) 13.44 (− 1.44, 28.31) 0.077
6 months 59.67 ± 30.9 50.1 (39.82, 60.39) 51.67 ± 34.2 36.17 (25.42, 46.92) 13.94 (− 0.94, 28.81) 0.066
12 months 58.67 ± 31.4 49.1 (38.82, 59.39) 53.33 ± 36.14 37.83 (27.08, 48.58) 11.27 (− 3.61, 26.15) 0.138
24 months 67.88 ± 33.68 56.95 (46.17, 67.73) 58.77 ± 38.79 41.54 (30.26, 52.81) 15.37 (− 0.23, 30.98) 0.053

SD standard deviation; 95% CI, 95% confidence interval; VAS visual analog scale; ODI Oswestry Disability Index; EQ-5D European Quality of Life-5 Dimensions

* Statistically significant difference compared with preoperative value (P < 0.05)