Table 2.
The 5 subthreshold and 8 suprathreshold electrophysiological properties with their corresponding average values and contributions to the first 3 principal components from PCA performed separately for sub- and suprathreshold electrophysiological parameters (eigenvalues PC1–PC3, n = 137 cells from 41 mice).
| # | Description | Mean ± SEM | PC1 | PC2 | PC3 |
|---|---|---|---|---|---|
| 1 | Vrest: resting membrane potential | −71.82 ± 0.59 mV | 0.46 | 0.48 | 0.54 |
| 2 |
m: membrane time constant |
35.26 ± 0.86 ms | −0.47 | 0.26 | 0.01 |
| 3 | R IN: input resistance | 122.23 ± 2.57 MΩ | −0.25 | 0.71 | −0.52 |
| 4 | Sag ratio: Sag in percentage | 7.06 ± 0.31% | −0.17 | 0.39 | 0.51 |
| 5 | Rheobase: minimal current necessary to evoke spike | 115.7 ± 5 pA | 0.69 | 0.2 | −0.42 |
| 1 | APVmin: minimal membrane voltage during AHP | −48.81 ± 0.41 mV | −0.11 | 0.5 | −0.04 |
| 2 | APVpeak: peak membrane voltage of spike | 46.1 ± 0.69 mV | 0.71 | 0.08 | 0.04 |
| 3 | APVthresh: threshold voltage at spike initiation | −33.96 ± 0.26 mV | 0.2 | 0.11 | 0.77 |
| 4 | APVslope: the maximal slope of the spike | 141.75 ± 3.05 mV/ms | 0 | −0.23 | −0.01 |
| 5 | APVhalf: membrane voltage at spike half | 6.07 ± 0.37 mV | 0.12 | −0.22 | 0.29 |
| 6 | APVamp: amplitude of the spike | 80.06 ± 0.72 mV | −0.5 | −0.13 | 0.54 |
| 7 | AHP: maximal amplitude of AHP | 14.85 ± 0.41 mV | 0.39 | −0.44 | 0.07 |
| 8 | APfreqmax: maximal spike frequency | 9.99 ± 0.37 Hz | −0.16 | −0.65 | −0.14 |