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Effects of Bromelain on the production of IL-6 and IL-8 in the AGEs-treated HGFs. The AGEs-elicited secretions of IL-6 (A) and IL-8 (B) in HGFs were downregulated in response to Bromelain treatment (0, 2.5, 5, and 10 μg/mL) in a dose-dependent manner. Data represent the mean ± SD. ∗P < 0.05 compared to control group; #P < 0.05 compared to AGEs only group.
