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Effects of Bromelain on the cell senescence activity in the AGEs-treated HGFs. The cell senescence activity was up-regulated after stimulated with AGEs, measured by the increased expression of β-galactosidase (SA-β-Gal) staining and p16. Bromelain treatment (5–10 μg/mL) then reversed the increased cellular senescence. Data represent the mean ± SD.
