Table 1.

Clinical A. baumannii isolates included the in vivo model

Isolate	Genotype	CFDC MIC	CZA MICa	MEM MIC	SAM MIC
AB 147	OXA-23-like (PCR)	2	>64	64	32
AB 230	ADC-33, OXA-82	2	>64	32	4
AB 237	ADC, OXA-58-like	2	>64	16	8
AB 97	PER-1, OXA-58, ADC-76, OXA-68	8	>64	4	16
AB 319	ADC-Type, OXA-829, OXA-24	8	>16	>16	8
AB 318	ADC-33 (V317G variant), OXA-23, OXA-82	32	>16	>16	16
AB 320	ADC-33 (V317G variant); OXA-23, OXA-82	32	>16	>16	8
AB 313	PER-1, ADC-25, OXA-23, OXA-66	>32	64	64	32
AB 314	PER-1, ADC-11, OXA-66, OXA-72	>32	64	64	32
AB 316	ADC-25-like, OXA-66, OXA-72, PER-1, TEM-1D	>32	32	>64	32
AB 323	ADC-25-like; OXA-172	>32	>64	16	16
AB 324	ADC-11; OXA-66; OXA-72; PER-1; TEM-1D	>32	>16	>16	64
AB 325	ADC-25-like; OXA-9; OXA-24; OXA-51-like; TEM-1A; VEB-9	>32	16	>64	32
AB 326	ADC-25-like; OXA-82	>32	>64	16	2
AB 327	ADC-25-like; OXA-66; OXA-72; PER-13	>32	>64	64	8

CFDC = cefiderocol, CZA = ceftazidime/avibactam, MEM = meropenem, SAM = ampicillin/sulbactam

Avibactam concentration fixed at 4 mg/L.